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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4749bcc3e9b95d856ab0dc7083024c9d5c6b28748831d978a2220b8faf44fd1c' 
  AND token = 'Jb5D6nIY5V+GG8dXN1rFctkRTDF6NMOQQoWUTZ7gCf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}