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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a98130de250a0ab56a7969c1f55f1594067b70b3b277740a43ec7f4aae4b13a0' 
  AND token = 'B/br3VZMDPFkvRYW54s5AhF/aiJOTj0zyzBdXv2Wme4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}