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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '297f6f1c1e2ff742d0b4f7bdfdce0b0ed7c266ca2e85e14e1ddd231a5197198f' 
  AND token = 'ptYBkSV+ChV83Y8YmvZjilqPDbMi8ORaYtmu2fL0gjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}