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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7523e100a4ca57313ad2b30bc1fc78c2de94cfabaabd825f977aa113f02e1acd' 
  AND token = 'gPHj+EkI7q9GFJR+nB6/vMXtFhu3ypf78tUFIA2wWuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}