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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '331dc588d897a439dd26644d3b965c578869e20aaa0e51aa11a3af6e844fa25b' 
  AND token = 'Nmo5a52elNVpK2PSXGb0kUrAH6FDB3aAKrlz2wvU4Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}