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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c2eeb0007d8a133d0a029af6fffa4e50a324b9e9253d482d40901d055dbd774' 
  AND token = '7ueb2Eh3aAvOWy7s3Golf2f8Fj/B127rBgvzYJmhRBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}