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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7462e381e5ec45474d4fe897eb606a3cf995afbe303772a2e67c681cae2b107' 
  AND token = 'FR8iYus/aOeqEM2D3d48SmHXw1aRUhGXG8C8NER1PA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}