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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c840fb37cd07b5dbc1147d2393258bba696fce0ffd0780a480dfea4d22fa05d7' 
  AND token = 'XFsuoBAqh5j5wCEZB2n9Z/9NXJXlByxS32ld1U71Ixw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}