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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33368dcb75255c5a358f17e83d1451322db5c81c5e3263b1f4c1f12bcfe45d33' 
  AND token = 'DJhdEOrtl4Hn9p72VEconbj25eVJwCAIG81cfCFb6Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}