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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9cb68a2572e7c0a980f10470730e5618cff892b40b28c1f82b5662f7a9c34c2' 
  AND token = 'xMK4QgJ64V6LCZBox6VTIMS8DsAsBraC9IrgFzjFLo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}