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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e886d8e3da1b4909139dfffd9681338283129a6e4a2c8c25610913a757c2304' 
  AND token = 'Q6VUmpSLxojntYpUpFYay+Q9H61aKl6k1chaXD1w0ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}