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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5268e56af1adc0982975dd8d6741929e868a3992a0b61546ec1aa67635547545' 
  AND token = 'Pq/FOBl9XWhpQa4nMxaxcil7tuzQEAth1OWeVV9p+o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}