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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af216c1e26545549d2be1a1d68445cdc6f903b235a79728d0c64a24d220172cc' 
  AND token = 'buwSK5B7EpTOfZYVlF5ASWmaysJLOpYzQxSQWaIeM78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}