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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e6180e0d6c1b2b8749b52cda0a514e811870a25c38bceda4da7cff77c5fad22' 
  AND token = 'AX12rqsAlymqgHJA/cnHhn8BJxbGmT/V4jKP4hPtdPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}