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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9ff1724315376cb9c8e834543916e30aed343dc2312ed0e7d12f721e2d0580' 
  AND token = 'zQGq7Q1OQ8nkLqPAg1kn97zxP7SN9zBUZF1HibjI3ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}