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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fbdcb2b8de5827e587b699b5c2e960a8e1d85f8c7934277345e9fea31f3f280' 
  AND token = 'wutqU709B2uTNxNU8x37xPsvAUUEcXHaxePvSgTmyO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}