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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5f8609baff71ec64b363615a7189a593dd9ee0500f4eb12f9aad70392d75b5' 
  AND token = 'rnUcf8b2L8mRC22jAZs3D8iLiC17XEQ4Xyh6HgteDj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}