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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78daf3158e7d96e2a6bdeb2a4f3ef18fb823bf68deb34adcd5566f23c01de02' 
  AND token = 'KjdtY7RGD0FrjGFR6po6zdWo1uM1b9BUaALOa6IU0jQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}