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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b0d7a97754a6b7e092be2beeb11df87127ad0692e4b32bc5a930fbff58d4483' 
  AND token = 'ROxOsR8zGeUeXwxE7bpAqwYtzXuCOW4aDUCBL0Ietl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}