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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cad743dacf261ae7077621b1f007d4bbe07e3163746ff052cd1f4571f499b0cc' 
  AND token = '0IawqrAIpyhCh4rGF9mFjLBk/EnVF95NMsB4a6ou2DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}