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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5df4034c41bd19700bb8c94fdf67c7c2b5eb640ffb4f4f8b9f305949f326cdc0' 
  AND token = 'hIbstu1uMBbzFHSrgSOAsP3O9f5EsCzOxwRDgejl18k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}