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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d04d6c5dc77e3bb6c097311ac7006bf506a8983b0920ee6b63d6c2539a417af' 
  AND token = '0a1WmTTcI0dFSrMQgWJe4arIxjX+X4NTJJVvxqgQj+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}