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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d0bd81593402eb13de01102113e25f1df0194f1e0093547e763c73b3c2dffaa' 
  AND token = 'TO33ncQoaP9MMxy40ekP0XtMbQMD1phErMP0h5wMjq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}