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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ccce61cc6d6acbcb60d0d0c9319c52e18ff6cc0d16f1c1d5b91d564d156eb49' 
  AND token = 'wrGUGB22s+bau8h/zd1MflZ+LxK7aWnRLYcB54Zd9zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}