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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '278db58e2c48334847029c3d4277baa155332bbbaff274dd2f7a72dccea485d1' 
  AND token = 'QMxMdp4Pya6Pk5AuNaSP6SFZF+bhb7ncoAM1f7/J9TI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}