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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3334859725adca4f8b0b1c505b0f3f6e53e44d51879701f1dc01a0a6cf715ea' 
  AND token = 'g5dSMmJPLQmZh/1upi1YglSgfjHPY3Z/wp0Au2ghD7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}