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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a584454c6bbc73889cc22a5afd9adc898472f7d08608360fa9fa008fd98e8f40' 
  AND token = 'Zj6SL6+cQkJrI9CM8z9E6XRw3InFR9PWkVy6UB2Z8QY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}