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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ba0f596694012c557895eb84914ae3ed0008da63ce144cde09dc8b6f7d5e05f' 
  AND token = 'TKeM5RNYDmYruIghnIbTnXnRuqAvYHeZ1RY/LudA49Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}