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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e875ef50ce62699881798552abdd2671429e12d76a2ab121110d877f162aeafb' 
  AND token = 'ogn6FaCnEZWSN4I5rB2xinsOTBdgtuoNZpgdmB3eVrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}