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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04a0a3d6cd12e1353007844f00a4f10096e5a3ab0850568d722b93bec794ac45' 
  AND token = 'F1sQ2czCK0fsH4uyY+TFTBZt6KEct+q0gD07PuE75jY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}