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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5043c1d9114c2d0087ac522f4f37ddd8583ad23278f4bc6a7748d18e65ba8c73' 
  AND token = 'Xtk0ITerH7k9wkk8z3wynkT0BqdKyF/l1JvBgWpwep8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}