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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b613889de5fce0fee7bc16445bd1b38078ee2ddf778124cec2f0e613c1778713' 
  AND token = '0BZBtQxblIDijXulk6U3oH5KgUnqAPQ1oHFr/S3A+oQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}