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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d0ea02004e5ae195a0a3e38c8a998378631a476ad5740ceaed18162d6b59557' 
  AND token = 'YwdlGF8g0UJR2XyV1sM3PCASyvDGWanGgMyhZTfPGZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}