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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ac22cd345dc79e753b0014eedbcfb184e427f9a42c2720ccbfd850fc107fbc9' 
  AND token = 'ZypgX7XtNVgHoNzyVJ0OzvqseXM1XpDSvuOJSpVYPUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}