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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f5f4c77accec21800b1a53140f5e217d588a3cee9ee4b3531753d2277af09f4' 
  AND token = 'meR+ESzDzOHlld0VZoIdxy1R5Ol9CT1bsv77RxASliI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}