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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02afa9fc9296a399d4e2270a7b5aa42580a405cf03bb49470c7d0e16ce8583bb' 
  AND token = 'Tj3O3O22+qosQnq4NtbFlxKd0FEPetmZ2kFZWdKdCdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}