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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '323f72b0acc080684f61c8aec3d425cc24556e70af4971d8aa782cae656e17c2' 
  AND token = '3A5wYr/egBfEulfnvBo/LlYZhnsulCaGlfik8SD16L4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}