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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cea38b2daa14862b515efbdf997ab002d4dbaf2bdb21d644b810fe46b7f9b327' 
  AND token = 'KqYQx+vecUrWRk/MG1xQ5kMhm2lt8Zmf5841I7TpPXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}