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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457b6cdd81c04daeb7085266b3ef7b2929f6a232717a33d2136497b50119acf8' 
  AND token = 'gyRJsxQ1b8upTbykwjIdLN/y0vXFK57vOtkapF91zBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}