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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec729c1e4a5fa77fc671dd2c96acea0399083fac247b848201c47ab515d8e5ac' 
  AND token = 'x0ppOGCyjuEZ/+8q9Fc+0TtrPlcFGXN5iS65Z8gI2i0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}