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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df46b34fc28cd06c43b164df6ac2b1f5453b491f210e5d62da3bcd5691989662' 
  AND token = 'i29lIOZQ4yoO6DQxGmm2+W1ehvERvv3PFZ8Z10ntwM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}