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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41898f66732d9e4bae00f9f5fa7ed4f978074a18e434004d73e9f86354a2a351' 
  AND token = '5tzcF0zoAD6c9ezrxO/U7fzAmtzNC6BlBER6AmTY06o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}