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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '401a1efbca6d4464459c783e671eebd150e567351208d0ff4f4d276d5437ec8f' 
  AND token = 'LUDW78ju696/faP83C3Iso4dkkKWg9XUASFvbEj96ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}