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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d198a7e70b0981a3791a455159c388e1dfe206073c9cf1358f3b96d572ca0bb' 
  AND token = '3+rAOZzNvZwawRFEY0uSjjKkSeu9Ao6dsO8Lx3kf9sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}