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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a22c63c8a134641c5333fcd483996eed009f7567af96f6a1330a47ce895346' 
  AND token = 'wGN6Ok3zOy2dMEEBU5jqUSJaVjFjXvdcc6dOghuXZ+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}