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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14c27199189d04ada8c5a0601dfeb20b38213b2dcf38fbe969da08cb295406c3' 
  AND token = 'oUd41nmMatea9dx4sN71fcuBYCgxa/BMPy2vSlrjj4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}