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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3d9ff16ebf6594e689d587a6374cdbfdebdb5b462c046bcf49b5dfbb4b3db61' 
  AND token = 'X4FWsHHdcuU1NH/uYoyY/mwcuWeU02zwf8bjNZI2wJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}