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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88653f826b6c082e25718e55038c78c3b1683add03540610ad0494b14d09f41e' 
  AND token = 'eh37TJb5gr4+QytrxYgkmV7rIesR4WUSAPnzn+0nhkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}