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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4563a9820cfda08936a084ba011c9a7bf5e1289f00e0fd5439a0e3c0f5fb5eb3' 
  AND token = 'nDCSPmP0Lp3HE4QVKJGGOslboizPs0xoxX9LUJiM/Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}