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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72c8ef1ae931345468fe7274e3c289a08e430e39fd9868f3441d64663fdfa44' 
  AND token = '7I2c6mNta0J6Nxbo5qvKB67+sR6bKrMJnLmjjLUYOnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}